9^th Global Chemistry Congress July 23-24, 2018 Lisbon, Portugal

Biography:

Lali Gurchumelia is a Chemist, Doctor of Technical Sciences and works at the TSU Rafael Agladze Institute of Inorganic Chemistry and Electrochemistry, Georgia. Her scope of scientific interests is Chemical Science, Chemical Engineering, Ecological Engineering, and Ecological Biotechnology. She has 55 publications and in the last 10 years she has participated in five scientific grants. Currently, she is a Manager of the grant # 216770 - “New type fire-extinguishing powders and foam-suspensions based on local mineral raw materials” funded by the National Science Foundation. She has participated in many international conferences and congresses: Nürnberg, Germany; Toledo, Spain; New Forest, UK; Montreal, Canada; Istanbul, Turkey; Elenite Holiday Village, Bulgaria; Rome, Italy; Paris, France; Yerevan-Vanadzor; Tbilisi, Georgia and Ureki, Georgia. She has many years of experience in the study and evaluation of fire–extinguishing and fire- protective materials.

Abstract:

The aim of the present investigation is to develop a technology for production of novel, halogen-free, environmentally safe, highly efficient fire-extinguishing powders based on local mineral raw materials, which does not require modification with expensive, halogen-inclusive, hydrofobizing additives and providing low-cost production of fire-extinguishing powders in comparison with imported analogues. The optimal dispersity was selected in such way, that caking capacity is minimal and a homogeneous action of combustion products on the flame as well as a heterogeneous inhibition of combustion process must take place. The evaluation of powder efficiency is carried out with consideration of both effects. Experimental data confirm that the developed fire-extinguishing powders are characterized with high performance characteristics, as well as high fire-extinguishing capacity. At the same time it should be noted, that the efficiency of the obtained powders is practically the same as of standard imported powders, but do not contain any halogens, should be environmentally safe and 1.5-2 times cheaper than the imported analogues. For obtained powders, the conditions of extinguish optimum and effective use of powder are stated. Optimum extinguishing condition means the selection of optimum intensity of powder supply into seat of fire when minimum consumption of powder provides fire extinguishing in minimum time. Thus, in order to determine optimum conditions of extinguishing it is necessary to study the dependence of powder specific consumption and extinguishing time to supply intensity. For our powders optimum condition of extinguish is: powder supply intensity I-0.6-1.0 kg/m²sec to fire center when powder specific consumption does not exceed G=0.8-1.2 kg/m². Therefore, we can surmise that the use of fire-extinguishing powders of our preparation is possible to extinguish all types of fires over ground, as well as, at underground constructions and does not need additional antiseptic measures.

Biography:

Maria Helena Casimiro has completed her PhD in Chemistry from Lisbon University. Her work has been focused on the functionalization of macromolecules (polymeric and hybrid materials) tailored for applications on biomedical, environmental, and conservation and restoration areas, using gamma-radiation as a modifying tool. She has been involved in national and international projects, students’ supervision, worked as Reviewer for journals of international circulation and co-organized science promotion activities.

Abstract:

Radiation processing techniques are based on the physical interaction of radiation with matter which is capable of promoting specific chemical reactions. In particular, gamma irradiation, a clean and environmental friendly technology (as there is no need of solvents, initiators or high temperatures, leading to any residues) has been successfully applied over the years in the preparation/modification of polymers. By suiting the experimental conditions like irradiation method, dose rate, irradiation atmosphere, samples’ absorbed dose, reactants’ concentration, etc., it is possible to functionalize polymeric based materials, tailor its properties and adequate them to different applications (mainly through polymerization, crosslinking and/or grafting reactions). In this presentation, the methodology that our team have been carrying out on the development/functionalization of chitosan based matrices and PVA based membranes respectively for biomedical applications (wound dressings) and for catalysis (polymeric catalytic membrane reactors for biodiesel production), using gamma-radiation as a modifying tool will be highlighted. Relevant results will be presented.

Biography:

Goncagül SerdaroÄŸlu has completed his PhD from Cumhuriyet University (2008) and postdoctoral studies from Auburn University (2014). Her research interests are on the electronic structure methods and their applications to the medicinal and pharmacologically important molecules. Recently, she has also focused on spectroscopic investigation of organic molecules by using computational tools.

Abstract:

The indole alkaloids and heterocyclic aromatic compounds have a vital role in research fields such as chemistry, pharmacology and biology etc. because of the structural properties of them, they have acted (agonist or antagonist) on variety of receptor sites on CNS (central nervous system). Recently, the computational tools are getting commonly used to explain the reactivity behavior of a specific molecular system. All quantum chemical calculations by using the DFT method with G09W package [1] have been conducted at three basis sets and ten solvents to look for the basis set and solvent effect on the chemical reactivity behavior of each studied aromatic heterocyclic compounds. The solvation phase simulations have been performed by PCM (Polarized Continuum Model) [2]. The aromatic substituent group effect on the intra-molecular charge transfer of the basic structural unit have been evaluated by NBO analysis [3]. The functional group vibrational modes verifying by GausView 4.1 [4] program are a good agreement with the literature data. The HOMO, LUMO and MEP diagrams have used to predict the nucleophilic and electrophilic attack sites of each studied compounds. The physicochemical parameters and quantum chemical parameters of aromatic substituted compounds have been calculated to compare with the basic structural unit the chemical reactivity behavior of all compounds, too [5]. All calculations have been conducted at TUBITAK ULAKBIM, High Performance and Grid Computing Center. The author thanks to Scientific Research Projects Department of Cumhuriyet University (Project No: CUBAP: EÄžT-066).

Biography:

Edit Csapó is a Senior Research Fellow at MTA-SZTE Biomimetic Research Group, Department of Medical Chemistry, University of Szeged, Hungary, and Assistant Professor at the Department of Physical Chemistry and Materials Sciences, University of Szeged, Hungary. She received her PhD degree in chemistry at University of Debrecen in 2010. Currently, her research interests focus on the preparation and characterization of noble metal-based nanohybrid systems, protein-, polymer, biocompatible surfactant-based drug-containing nanocomposites and surface plasmon resonance investigations. She has published nearly 40 papers in reputed journals (more than 105 impact factors and sum of times cited 400).

Abstract:

Gold nanoparticles (Au NPs) and gold nanoclusters (Au NCs) having characteristic plasmonic or highly photoluminescence features have become one of the most important types of nanomaterials that have been extensively investigated in many fields. The sub-nanometer sized Au NCs show unique physical and chemical properties such as well-defined molecular structure, discrete electronic transitions and characteristic size-tunable photoluminescence. Most of the protein-stabilized Au NCs exhibit intense red photoluminescence (λemission ~ 650 nm) which originates from the icosahedron gold core and partially independent from the applied protein.

In this work presented here, we highlighted the biocompatible fabrications of Au NPs and Au NCs using proteins (bovine serum albumin (BSA); lysozyme (LYZ), gamma-globulin (γG)), nucleotide (adenosine monophosphate (AMP) and amino acids (histidine (His); tryptophan (Trp), cysteine (Cys) which result in different nanostructures having tunable blue, green, yellow and orange emissions. The main goal of this work was to investigate the spontaneous interactions of AuCl4- and the studied biomolecules as well to optimize the gold/ligand ratios and pH on the formation of gold constructs. Based on the experimental results we provided important information on the gold intermediates and the formation mechanisms of the plasmonic or fluorescent nano-objects. Moreover, the fluorescent Au NCs were used for selective detection of different transition metal ions (e.g. Fe3+), anions and small molecules in aqueous solutions.

Biography:

Hasratyan Ani has received her Master’s degree from Chemical Faculty of Yerevan State University in 2013 under supervision of T Ghochikyan. She received her PhD in 2017 under supervision of Dr. M Sargsyan. During her scientific work, she has done a lot of experiments and has 24 published articles. Her research interest is in NMO/H₂O system and its chemical properties in applied organic synthesis. She participated at 4^th International Conference of Young Scientists “Chemistry Today-2014”, Yerevan, Armenia, 18-22, 2014 and IV Scientific Conference of the Armenian Chemical Society “Achievements and Problems”, October, 7-11, 2014, p-158, Yerevan-Vanadzor.

Abstract:

In the literature, N-methyl-N-oxide is known not only as a solvent for cellulose but also widely used in organic synthesis, in particular as a co-catalyst in oxidation processes but as a medium for nucleophilic substitution reactions it was previously unknown. In 2015, it was shown for the first time that in the NMO/H₂O system in the presence of bases; azoles can easily be alkylated with various alkyl halides. Subsequently, in our paper, it was shown that with the aid of the above described system it is possible to successfully carry out the dehydrochlorination of chloroethyl azoles, which leads to the formation of vinylpyrazoles. This method has allowed avoiding the conduct of dehydrochlorination in an alcoholic medium. Subsequently, in the above described system, allylation of multifunctional nucleophiles, in particular phenol and monoethanolamine with various allylic halides, was carried out and it was shown that the NMO/H₂O system is an effective method for alkylation compared with interphase catalysis. The NMO/H₂O system can also be used in hydrolysis reactions. The hydrolysis of 1,3-dichlorobutene in this system was studied and it was shown that the hydrolysis product undergoes alkylation and results in the formation of unsaturated ethers. Synthesis of similar ethers is described in the literature in much more complicated ways.

Biography:

Ahmed Mohamed Youssef Mohamed has completed his PhD at the age of 34years from El-Azhar University, Egypt and postdoctoral studies from National Research Center. He is a researcher in national research center from 2014. He has published more than 9 papers in international journals.

Abstract:

Dielectric properties and ac- conductivity was studied and correlated with the structure for a series of YBCO ceramic doped with different doping level ranged from 0.1- 0.5 wt. % of non-magnetic nano metal oxides, namely CuO and SnO2. The most important feature of this study is the ultrahigh values of dielectric constant at low frequency exactly 50 Hz, where we found that undoped YBCO has a value of ε equal to 6.99x106 at 50 Hz which is higher than any other ferroelectric material. The highest value of ε' for doped YBCO samples is recorded for 0.2 wt.% CuO- YBCO whereas for SnO2 -YBCO the highest value is for 0.4 wt.%

Also, the values of ε' depends on the nature and magnetic properties of the doped metal oxides. This work contributes to the materials with ultrahigh dielectric constant, i.e. values of the real part of the permittivity έ exceeding 1000. Since long, materials with ultrahigh dielectric constant are in the focus of interest, not only for pure academic reasons but also because new ultrahigh- έ materials are urgently sought after for the further development of modern electronics. In general, for the miniaturization of capacitive electronic elements materials with ultrahigh –έ are prerequisite. Moreover, ac- electrical conductivity has two frequency dependent regions, the low frequency one where σac is independent on frequency whereas at high frequency region dispersion occurs. All samples are found to follow the universal power law and have a typical fit. The exponent S is less than unity and decreases a little with increasing temperature which suggesting that the hopping of electrons between the barriers is the predominant mechanism for the conduction.

Biography:

Dr.Widad completed her PhD degree in Phytochemistry from the University of Reading, UK .She is appointed as assistant professor at the college of Phamacy, Al-Mustansiriya University, Iraq in 2004 and currently she is dean of the college of pharmacy from  Al-Mustansiriayah university. Her research interest includes Photochemistry, pharmaceutical chemistry, and chromatography. She has published several number of papers in reputed journals in the field pharmaceutical chemistry.

Abstract:

Chenopodium album L the Greek name Chenopodium means goose foot. The plant is native to Asia and Europe.  The analysis of the constituents of the plant was performed using Gas chromatography and HPLC techniques. The presence of kaempferol was detected by TLC and HPTLC in comparison with standard kaempferol. Kaempferol 3- O- β- glucoside (astragalin) was detected as the major glycoside in the polar fraction by TLC and HPTLC comparing with astragalin standard. Astragalin was isolated from Iraqi plant as yellow powder by coloumn chromatography and further purified by preparative TLC and combined with isolated astragalin from preparative HPLC. Further identification of the compound was performed by ¹H-NMR spectroscopy. Sterols of the plant were analyzed using GC MS analysis. The major sterols with M^+ 416 could not be identified by the data base even the similarity index was 81.

 

Biography:

Dave Pasin has long recognized the need for innovative technologies that lessened environmental impact whilst improving the occupational health and safety of workers and end users. Dave Pasin founded TBF Environmental Technology to develop and manufacture VOC compliant, low toxicity solvents for industry. Mr. Pasin began development of his first VOC-Compliant solvent replacement in 2011. The solvent he developed to replace Methyl Ethyl Ketone (MEK) took over 2.5 years to develop. The ground breaking research and development led Mr. Pasin and his team to also develop safe, effective, VOC-Compliant alternatives for Xylene, Toluene, Acetone, Heptane, Hexane, non plasticizing coalescent solvent and glycol ethers. Mr. Pasin is very active in his community, participating in various amateur sports, coaches football, and is involved in many civic, community and service organizations such as Lions serving as a director for the Vancouver Fire & Rescue Service and Lions International.

Abstract:

The purpose of this presentation is to discuss and detail advances in VOC compliant solvents. The presentation will outline a variety of new, VOC compliant solvents, their efficacy, how they may perform and where they may be used in paints, coatings, adhesives and cleaning formulae. The presentation will also discuss the development and efficacy of new VOC Exempt low toxicity replacement for a variety of Glycol Ethers and a film forming coalescent and their use in formulation.
  
 

Biography:

L. BALAN obtained the PhD degree from the University Henry Poincaré in Nancy, France, in 2005. Her PhD was devoted to the elaboration of an original material for the anode of Li-ion batteries. After a post doctorate in Orleans and then in Mulhouse, she joined the Department of Photochemistry (DPG) of Mulhouse in 2006 as a CNRS Senior Researcher. She opened a new field of research in this laboratory, viz. the photoassisted synthesis of metal nanoparticles and metal-polymer nanocomposite materials.

Since December 2009, L. Balan joined the Institute of Materials Science of Mulhouse (IS2M) CNRS-UMR 7361. She has published more than 100 papers, 4 book chapters and 5 patents. Dr. L. Balan has been serving as an editorial board member for few scientific journals.

Abstract:

The metal nanoparticles and metal/polymer nanocomposites film obtained in this way were characterized and the influence of several parameters (fluence, exposure, silver ions concentration and nature of the free radicals generator) on their formation was evaluated [2]. This photoinduced synthesis offers substantial advantages since it combines the characteristic features of light activation i.e. versatility and convenience of the process, high spatial resolution and reaction controllability (intensity and wavelength), with the simplicity of the colloidal approach. Moreover, the use of amplitude masks or interferometric devices to shape up the light beam used to induce the photoreduction of silver cations provides a very powerful and versatile means to spatially manipulate metal nanoparticles.

Biography:

Hasratyan Ani has received her Master’s degree from Chemical Faculty of Yerevan State University in 2013 under supervision of T Ghochikyan. She received her PhD in 2017 under supervision of Dr. M Sargsyan. During her scientific work, she has done a lot of experiments and has 24 published articles. Her research interest is in NMO/H₂O system and its chemical properties in applied organic synthesis. She participated at 4^th International Conference of Young Scientists “Chemistry Today-2014”, Yerevan, Armenia, 18-22, 2014 and IV Scientific Conference of the Armenian Chemical Society “Achievements and Problems”, October, 7-11, 2014, p-158, Yerevan-Vanadzor.

Abstract:

In the literature, N-methyl-N-oxide is known not only as a solvent for cellulose but also widely used in organic synthesis, in particular as a co-catalyst in oxidation processes but as a medium for nucleophilic substitution reactions it was previously unknown. In 2015, it was shown for the first time that in the NMO/H₂O system in the presence of bases; azoles can easily be alkylated with various alkyl halides. Subsequently, in our paper, it was shown that with the aid of the above described system it is possible to successfully carry out the dehydrochlorination of chloroethyl azoles, which leads to the formation of vinylpyrazoles. This method has allowed avoiding the conduct of dehydrochlorination in an alcoholic medium. Subsequently, in the above described system, allylation of multifunctional nucleophiles, in particular phenol and monoethanolamine with various allylic halides, was carried out and it was shown that the NMO/H₂O system is an effective method for alkylation compared with interphase catalysis. The NMO/H₂O system can also be used in hydrolysis reactions. The hydrolysis of 1,3-dichlorobutene in this system was studied and it was shown that the hydrolysis product undergoes alkylation and results in the formation of unsaturated ethers. Synthesis of similar ethers is described in the literature in much more complicated ways.

Biography:

Lali  Gurchumelia, Chemist, Doctor of Technical Sciences. She works at the TSU Rafael Agladze Institute of Inorganic Chemistry and   Electrochemistry  (Georgia). Scope of scientific interests: chemical science, chemical engineering, ecological engineering, ecological biotechnology.  She has 55 publications, including in the Infactactatorial Journal -12. The last 10 years she has participated in 5 scientific grants. Currently, she is a manager of the grant # 216770 - “ New type fire-extinguishing powders and foam-suspensions based on local mineral raw materials “  funded of the National Science Foundation. She has participated in many international conferences and congresses:  Nürnberg, Germany;   Toledo, Spain;   New Forest, UK; Montreal, Canada;   Istanbul, Turkey;  Elenite Holiday Village, Bulgaria; Rome, Italy; Paris, France;  Yerevan-Vanadzor;  Tbilisi, Georgia and  Ureki, Georgia.  She has many years of experience in the study and evaluation of fire–extinguishing and  fire- protective materials.

Abstract:

The aim of the presented investigation is the development of technology for production of novel, halogen-free, environmentally safe, highly efficient fire-extinguishing powders based on local mineral raw materials, which does not require modification with expensive, halogen-inclusive, hydrofobizing additives, providing low-cost production of fire-extinguishing powders in comparison with imported analogues. The optimal dispersity was selected in such way, that caking capacity be minimal and a homogeneous action of combustion products on the flame as well as a heterogeneous inhibition of combustion process must take place. The evaluation   of powder efficiency is carried out with consideration of the both effects.

Experimental data confirm that the developed fire-extinguishing powders are characterized with high performance characteristics, as well as high fire-extinguishing capacity. At the same time it should be noted, that the efficiency of the obtained powders is practically the same as of standard imported powders, but do not contain any halogens, is environmentally safe and 1.5-2 times cheaper than the imported analogues.

For obtained powders, the conditions of extinguish optimum and effective use of powder are stated. Optimum extinguishing condition means the selection of optimum intensity of powder supply into seat of fire when minimum consumption of powder provides fire extinguishing in minimum time. Thus, in order to determine optimum conditions of extinguishing it is necessary to study the dependence of powder specific consumption and extinguishing time to supply intensity.  For our powders optimum condition of extinguish is: powder supply intensity I-0.6-1.0 kg/m²sec to fire center when powder specific consumption does not exceed G=0.8-1.2 kg/m².

Therefore, we can surmise that the use of fire-extinguishing powders of our preparation is possible at extinguishing of all types of fires over ground, as well as, underground constructions and does not need additional antiseptic measures.

Biography:

Dr. Doan PHAM MINH has completed his PhD at the age of 26 years from IRCELYON (France) and postdoctoral studies from IFP (France) and IMT Mines Albi (France). He is now assistant processor at IMT Mines Albi (an engineering school in France). He has published more than 50 papers in peer-reviewed international journals and has been serving as an editorial board member of Waste Biomass Valorization journal.

Abstract:

Dry reforming of methane (DRM) consists of the transformation of CO₂ and CH₄ in to synthetic gas (sygas, mixture of CO and H₂) according to the following equation:

CH₄ + CO₂ → 2CO + 2H₂

            This process allows valorizing biogas, flue gas from incinerator and natural gas into syngas which can be used in various processes such as Fisher-Tropsch synthesis, methanol synthesis, H₂ production etc. DRM needs a catalyst because of the highly-chemical stability of CH₄ and CO₂. The main challenge of DRM relates to the deactivation of the catalyst. In fact, this process works at temperatures higher than 700°C at low pressure (close to atmosphere) to have exploitable kinetic. Under these conditions, metallic catalysts used for this process (i.e. nickel catalysts) are usually deactivated by the presence of side reactions.

In this paper, we present our last research on DRM process using hydroxyapatite supported nickel and/or cobalt catalysts. Hydroxyapatite (HAP, Ca₁₀(PO₄)₆(OH)₂) has advantages to be thermally stable up to around 1100°C, to be not water sensitive, to have controlled acido-basicity from the adjustment of Ca/P ratio as well as high specific surface area. The results obtained show that Ni/HAP and Ni-Co/HAP are very active and stable during long reaction time of around 300 hours. The relationship between the catalyst structural properties and their catalytic performance was built. The results are promising for the design of a performing catalyst for DRM process.

Biography:

Orsolya Gyulai earned her Masters’ Degree at the University of Szeged as a Researcher Chemist in 2015 and now she is a third-year PhD student at the Institute of Pharmaceutical Technology and Regulatory Affairs. She is going to complete the PhD degree in 2018. She has won several scholarships and presented  her research work in Spain, Germany, Sweden, Poland, the Czech Republic and also in Hungary. Her total impact factor is more than 4 at the age of 25. She has now 2 more publications under review. She would like to work for a pharmaceutical company, where she could benefit from what she has learned during the years.

Abstract:

Spherical crystallization is usually the last technological step in the production of solid form drugs. Not only purification can be achieved with it, but we can manufacture the optimal morphology of the crystals. Spherical morphology with suitable mean particle size is advantegous when direct tablet making technique is used. This way the amount of the additives can be reduced and smaller tablets can be produced. In our previous research (DOI: 10.1021/acs.cgd.7b00764) it was found that the spherical crystallization of ambroxol hydrochloride can be achieved by the non-typical methods, such as spherical agglomeration and cooling crystallization. Because of the spherical morphology, flowing and compaction properties of the powder have improved.

In the present work the parameter optimization of the spherical agglomeration method was further  investigated with the help of an FBRM probe, continuously observing the crystal growth in the non-typical crystallization systems. With this on line technique, it was possible to control the mean particle size and the optimal mixing time, and solvent-antisolvent ratio could also be determined. In case of the cooling crystallization, we applied an alternating temperature profile around the metastable zone in order to standardize the particle size. It was a heating-cooling cycle, so the smaller particles could dissolve when heating happened, then crystallize onto the surface of the larger crystals. With the FBRM probe, this process could be investigated and the exact, optimal length of the heating-cooling periods could be determined.

Biography:

Steffen Eller joined Chemspeed in 2012 as an Automation Chemist. From March 2015 – October 2015, Steffen Eller worked as a Workflow Architect before he became Head Workflow/Chemistry/Support and a member of the extended management board in November 2015. Prior to this, he was a Postdoctoral fellow at Max Planck Institute of Colloids and Interfaces in Berlin, Germany in the Biomolecular Systems group. Steffen holds a Ph.D. in Chemistry from University in Bayreuth.

Abstract:

The driver for medicinal chemistry is the demand for innovative medicines. Typically the growing need for novel active ingredients is accompanied by the search for targeted molecular diversity and novel experimental routes resulting in an increase of the synthetic work with the same amount of human resources. The only way to cope with this catch22 are flexible, modular, uncompromising automated solutions for library synthesis.

 

Following a brief introduction to concepts and Chemspeed’s innovation enabling technology, this presentation will focus on selected case studies from our customer portfolio such as:

 

• Synthesis of a triazole library using automated click chemistry.
• Development of a first generation MKP-1 probe.
• Discovery of an α-amino C–H arylation reaction using the strategy of accelerated serendipity.
• Synthesis of an oxazolidinones library using solid phase organic synthesis.
• Development of nanoparticle drug discovery vehicles.

 

Biography:

He graduated from the Nakhimov Naval School; Higher education received at the Physics Department of the Leningrad State University with a degree in "photonics"; thesis defended at the Moscow Academic Institute of Chemical Physics; he has over 20 years experience as a lecturer and conductor of the workshops and labs for the course "General Physics". Supervised 5 Ph.D students who have successfully defended their thesis in "Chemical Physics.

Abstract:

 I created the New Paradigm in Chemistry, which is based on my discovery of "Unitary symmetry of atoms, molecules, codons, mixtures". The essence of this paradigm consists in considering nuclei, atoms, molecules, codons, genotypes and mixtures as discrete objects. The subsequent analysis of discrete objects from the point of view of combinatorics makes it possible to generate an ordered homology system. The main feature of combinatorial homology system is the fact that certain portions of the two-link homology in the space of their physical and chemical parameters are arranged regularly, ie parallel to each other (symmetrically within the framework of certain transformations in the space under consideration). These regularities are represented as a system of simple linear equations. The main feature of this system of equations is the fact that by measuring only a small number of parameters of combinatorial objects of the class in question, the remaining parameters are easily computed, i.e. are predicted. The physical meaning of Unitary symmetry consists in considering combinatorial objects from the point of view of the hierarchy of interactions of elements forming a combinatorial object and compensating for weak interactions in two-link homology of substitutions. Within the framework of the Paradigm under consideration, a Combinatorial System of Chemical Elements (as a replacement for Dmitry Mendeleyev's table) was created, which allowed to discover a lot of erroneous data in NIST. The applicability of the analysis of experimental data to their reliability for an overwhelming class of molecules is shown. New reliable values of experimental data for ionization energies and thermochemical parameters are predicted. A Combinatorial System of the Genetic Code has been created, which allows us to consider mutagenesis and evolution at a simple mathematical level. The Combinatorial System of Genotypes and Phenotypes has been created, which allows to transfer Mendel's Laws from modern textbooks to textbooks on the History of Genetics. Consideration of hormone mixtures in four media (arterial blood, venous blood, lymph and urine) within the framework of the Paradigm under consideration made it possible to offer a model of digitizing each individual and predicting Pathology (Diseases) at the earliest stages of their development. At the same time, as a particularly important application, the solution of the problem of the relationship between the composition of hormones and the aggressive mood and behavior of the individual is considered.

Biography:

Abdeen Mustafa Omer (BSc, MSc, PhD) is an Associate Researcher at Energy Research Institute (ERI). He obtained both his PhD degree in the Built Environment and Master of Philosophy degree in Renewable Energy Technologies from the University of Nottingham. He is qualified Mechanical Engineer with a proven track record within the water industry and renewable energy technologies. He has been graduated from University of El Menoufia, Egypt, BSc in Mechanical Engineering. His previous experience involved being a member of the research team at the National Council for Research/Energy Research Institute in Sudan and working director of research and development for National Water Equipment Manufacturing Co. Ltd., Sudan. He has been listed in the book WHO’S WHO in the World 2005, 2006, 2007 and 2010. He has published over 300 papers in peer-reviewed journals, 200 review articles, 7 books and 150 chapters in books.

 

Abstract:

This communication discusses a comprehensive review of biomass energy sources, environment and sustainable development. This includes all the biomass energy technologies, energy efficiency systems, energy conservation scenarios, energy savings and other mitigation measures necessary to reduce emissions globally. The current literature is reviewed regarding the ecological, social, cultural and economic impacts of biomass technology. This study gives an overview of present and future use of biomass as an industrial feedstock for production of fuels, chemicals and other materials. However, to be truly competitive in an open market situation, higher value products are required. Results suggest that biomass technology must be encouraged, promoted, invested, implemented, and demonstrated, but especially in remote rural areas.

 

Biography:

Ahmed Mohamed Youssef Mohamed has completed his PhD at the age of 34years from El-Azhar University, Egypt and postdoctoral studies from National Research Center. He is a researcher in national research center from 2014. He has published more than 9 papers in international journals.

Abstract:

Dielectric properties and ac- conductivity was studied and correlated with the structure for a series of YBCO ceramic doped with different doping level ranged from 0.1- 0.5 wt. % of non-magnetic nano metal oxides, namely CuO and SnO2. The most important feature of this study is the ultrahigh values of dielectric constant at low frequency exactly 50 Hz, where we found that undoped YBCO has a value of ε equal to 6.99x106 at 50 Hz which is higher than any other ferroelectric material. The highest value of ε' for doped YBCO samples is recorded for 0.2 wt.% CuO- YBCO whereas for SnO2 -YBCO the highest value is for 0.4 wt.%

Also, the values of ε' depends on the nature and magnetic properties of the doped metal oxides. This work contributes to the materials with ultrahigh dielectric constant, i.e. values of the real part of the permittivity έ exceeding 1000. Since long, materials with ultrahigh dielectric constant are in the focus of interest, not only for pure academic reasons but also because new ultrahigh- έ materials are urgently sought after for the further development of modern electronics. In general, for the miniaturization of capacitive electronic elements materials with ultrahigh –έ are prerequisite. Moreover, ac- electrical conductivity has two frequency dependent regions, the low frequency one where σac is independent on frequency whereas at high frequency region dispersion occurs. All samples are found to follow the universal power law and have a typical fit. The exponent S is less than unity and decreases a little with increasing temperature which suggesting that the hopping of electrons between the barriers is the predominant mechanism for the conduction.

Biography:

Dr.-Ing. Jakob Albert is currently Assistant Professor (Habilitand) and Head of the Research Group “Biomass and Sustainable Production of Platform Chemicals” at FAU’s Institute of Chemical Reaction Engineering (CRT). He holds a Diploma (2011) and a PhD degree (2014) from the FAU in Chemical Engineering. Jakob’s key activities are in the research fields of biomass valorization, sustainable platform chemicals, polyoxometalate catalysts, and multiphase reaction systems. He is an inventor on 19 inventions disclosures and patents, and has received numerous scientific awards.

Abstract:

In the last decade, much attention has been paid to the desulfurization of fossil fuels. Due to environmental regulations fossil fuels have to be desulfurized to very low levels. Currently, the technology used for this purpose is hydrodesulfurization (HDS). An alternative approach to remove sulfur from fossil fuels is the oxidative desulfurization (ODS). In common ODS sulfur compounds are oxidized to their corresponding sulfoxides and sulfones. These oxidation products are significantly more polar and can be removed from the fossil fuel by subsequent extraction. A promising class of catalysts used for ODS are polyoxometalates. The most common oxidizing agent used in ODS is hydrogen peroxide. Only in some cases oxygen can be used as oxidizing agent. In comparison to HDS, ODS can be performed at relatively mild reaction conditions. Temperatures from 40-120 °C are sufficient for oxidative desulfurization.

In our recent studies, we investigate extraction coupled oxidative desulfurization using different sulfur-containing compounds (benzothiophene, dibenzothiophene, 4,6-dimethyldibenzothiophene) in different oil matrices (aliphatic, aromatic moieties) as the model oil and water as the in-situ extracting agent containing the dissolved polyoxometalate catalyst and oxygen as the oxidant.

Our studies show that all different sulfur-containing compounds can be completely removed from the oil matrix in a temperature range from 90-140 °C at 20 bar oxygen pressure. Moreover, they can be fully oxidized to water-soluble sulfur compounds. These sulfur compounds are extracted in-situ into the aqueous catalyst solution. Hereby, sulfate is found to be the major sulfur component in the aqueous phase. The other aqueous sulfur compounds are found to be sulfoacetic acid, 2-sulfobenzoic acid and 2 (sulfooxy)benzoic acid. Other non-sulfur containing decomposition products are carbon dioxide, carbon monoxide, formic acid, acetic acid and oxalic acid. We can demonstrate that the oil matrix has a major influence on the perfomance of the desulfurization. Additionally, the stability of the organic moiety under reaction conditions was proven and no catalyst leaching into the organic phase takes place. We systematically investigated the influence of different parameters such as temperature, pressure, water/oil volume ratio, concentration etc. in order to improve our oxidative desulfurization system. Our optimization studies showed that high water/oil volume ratios and high amounts of catalyst improve desulfurization of the model fuel significantly.

Biography:

She is the Ph.D.student at Mineral and Metallurgic Institute (ISMM), Moa, Holguín, Cuba.

Abstract:

Traditionally, the activated carbons (ACs) used in wastewater treatment are obtained from coal, lignite, wood or animal bones but, recently, the agro-wastes have received much more attention as a cheap source for ACs production. The employment of agro-wastes can contribute to the economic development and to reduce the environmental contamination particularly in developing countries. The eastern region of Cuba concentrates more than 90% of coffee and cocoa crops and there is a special interest in increasing productivity and cultivation areas. The cocoa and coffee husks waste could be converted into added-value products as ACs. In this region are also located the main metallurgic factories, dedicated to the extraction of nickel and cobalt from lateritic ores. During the production of nickel and cobalt mixed sulphides, it is produced the acid liquor waste (WL), which is poured with Ni(II) and Co(II) ions concentration much higher than the prescribed limits by industrial activities, thus leading to the health hazards and environmental degradation. The aim of this research is to study the adsorption characteristics of Ni(II) and Co(II) ions present in multi-elemental solutions, which simulates the wastewater from an acid leaching mineral processing technology with low cost activated carbon from cocoa and coffee husks and the conversion of the exhausted AC in others added value products.

Biography:

Maria Helena Casimiro has a PhD in Chemistry from Lisbon University. Her work has been focused on the functionalization of macromolecules (polymeric and hybrid materials) tailored for applications on Biomedical, Environmental, and Conservation and Restoration areas, using
gamma-radiation as a modifying tool. She has been involved in national and international projects, students’ supervision, worked as reviewer for journals of international circulation and co-organized science promotion activities.

Abstract:

Radiation processing techniques are based on the physical interaction of radiation with matter which are capable of promoting specific chemical reactions. In particular, gamma irradiation, a clean and environmental friendly technology (as there is no need of solvents, initiators or high temperatures, leading to no residues) has been successfully applied over the years in the preparation/modification of polymers. By suiting the experimental conditions like irradiation method, dose rate, irradiation atmosphere, samples’ absorbed dose, reactants’ concentration, etc., it is possible to functionalize polymeric based materials, tailor its properties and adequate them to different applications (mainly through polymerization, crosslinking and/or grafting reactions).

In this presentation, the methodology that our team have been carrying out on the development/functionalization of chitosan based matrices and PVA based membranes respectively for biomedical applications (wound dressings) and for catalysis (polymeric catalytic membrane reactors for biodiesel production), using gamma-radiation as a modifying tool will be highlighted. Relevant results will be pressented.

Biography:

Welyton graduated at the age of 21 in Industrial Chemistry at the Lutheran Institute of Higher Education in Itumbiara, Brazil. He specialized at the age of 22 in Production Engineering and Project Management at Candido Mendes University, Rio de Janeiro. With a developed career in Chemical and Food Industries, he is currently responsible for the departments of Industrial Hygiene and Chemical Products in a multinational Dairy Industry located in the State of Goiás, Brazil.
 

 

Abstract:

The variables involved in a cleaning and sanitization procedure are fundamentally time, temperature, chemical and mechanical actions. The search for the optimization of the correlation between them determines the effectiveness of the operation, and any change in value of one of them will result in a system rearrangement. Whereas some concepts such as cost reduction, process optimization and the search for continuous improvement, research rose the following question: Was it possible to optimize the process of cleaning Clean-in-place (CIP) of milk storage tanks and derivatives, reducing process parameters, maintaining efficiency and controlling chemical residual? With this line of thought, the research aimed to optimize the CIP process of milk storage tanks and derived from a dairy industry. The methodology was to optimize process parameters such as reducing the concentration of chemicals used, reducing the rinsing time, and display test deployment chemical waste. It was possible to first reduce the concentrations of chemicals used solutions (alkaline and acid) in 0,5%, representing an annual savings forecast with chemical approximately R$ 38 thousand. It was also possible to reduce some rinses times within the process that drawing a direct line to the flow of the rinse pump and the arithmetic mean of cleanups, we estimated annual savings of 84 million, 840 thousand liters of water. With the implementation of residual chemical indicator test, the process has become safer, because any alkaline residue or acid that the rinsing step can not be removed will be indicated in the residual test.

 

 

Biography:

He is a Professor in the Department Of Chemistry at Sri Vidyanikethan Engineering College, Jawahar Lal Technological University, Anantapur, A.Rangam Peta, Tirupathi, INDIA. Earlier he was NIH visiting fellow at karmonas cancer research institute, Wayne State University School Of Medicine. He was also a Royal Society Visiting Scientist in the Inorganic chemistry laboratories at the University of Oxford, UK, working on"Transition metal complexes as Anticancer Drugs". He has published 33 International publications and 31 international conference presentations including American Chemical Society conferences.

Abstract:

Cancer is a dreadful disease and any practical solution in combating this disease is of paramount importance to public health. Cancer patients have burdened by drug induced toxic side effects, and no turned to seek help from the complementary and alternative medicine hoping for a better cure. Research on Platinum based drugs and Non Platinum based drugs is a Multi-Million Dollar Industry in USA and there is every need to produce safe drugs for the cure of this monstrous disease. Flavonoids have a long history of use in traditional medicines in many cultures. The phytochemical, curcumin is one of the major dietary flavonoid, belonging to a group of flavonol, Curcumin is a natural polyphenol. It is highly potential molecule capable of preventing and treating various cancers.  Various dietary chemo preventive agents, turmeric powder or its extract are broadly used as therapeutic preparations in Indian System of medicine. We provide a summarized synthesis and structural determination of Curcumin Oxime, Curcumin Thiosemicarbazone derivative of Gold (III) complex. The use of these analogs for prevention of cancer tumor progression and treatments of human malignancies. A pharmacologic agent for treating and/or preventing cancer, among other diseases and conditions, and particularly breast, prostate, and pancreatic cancer, in humans and animals. The novel pharmacologic agent is an isoflavonoid or isoflavonoid mimetic covalently attached to a cytotoxic pharmacophore that, preferably has the ability to conjugate with a metal salt to form a more potent metal complex, particularly a Au (III) complex and other complexes of Platinum, Palladium, Ruthenium, Copper etc. My talk would mainly encompass different Transition Metal Complexes/Organometallic Compounds that are presently used as drugs, especially Anticancer and Anti-HIV drugs, apart from Anti-inflammatory, Antimicrobial, Antibacterial and diseases like Arthritis and Parkinson’s Disease etc. The talk would mainly focus on the use of Medicinal Chemistry and it’s application to Drug Design and Development in Pharmaceutical Industry, especially Transition Metal Complexes and Organometallic Compounds viz. Gold, Platinum, Palladium And Ruthenium apart from Copper, Cobalt, Iron,  Nickel, Zinc, Cadmium etc.

Biography:

Buxing Han, professor at Institute of Chemistry, Chinese Academy of Sciences (CAS); Academician of Chinese Academy of Sciences; Fellow of Royal Society of Chemistry.

He received B.S. degree in Chemical Engineering at Hebei University of Science and Technology in 1982, M.S. degree in Inorganic Chemistry at Changchun Institute of Applied Chemistry, CAS in 1985, Ph.D. degree in Physical Chemistry at Institute of Chemistry, CAS in 1988, and did postdoctoral research in Chemical Engineering at the University of Saskatchewan, Canada from 1989 to 1991. He was associate professor at Institute of Chemistry, CAS during 1991-1993, and has been a professor at the Institute since 1993.

Abstract:

Green chemistry is the future of chemistry and chemical industry. Biomass provides us a huge amount of renewable carbon source. CO₂ is the major greenhouse gas. It is also an abundant, nontoxic, nonflammable, easily available, and renewable carbon source. Conversion of the renewable carbon resource into valuable chemicals and fuels is an important area of green chemistry, which is also an effective route to the sustainable development of our society. However, efficient transformation of biomass and CO₂ into value-added chemicals and high-quality fuels is a long-standing task. 

In recent years, we are very interested in properties of green solvents and their applications in catalytic conversion biomass and CO₂ in green solvents. In this presentation, I would like to discuss some of our results[1-12].

Biography:

Dr. (Mrs.) Bertha Abdu Danja has completed her PhD in 2010 in the Brandenburg Technical University Cottbus Germany. Her PhD research was in the field of Environmental Chemistry. She worked for her Professor in the same University in Germany from 2006 until 2010 lecturing students and organizing their laboratory work. Dr. Mrs. Bertha Abdu has to date up to 15 publications in reputable journals. She is currently a Lecturer with the Federal University of Kashere, where she is the Head of Department of Chemical Sciences. She is also a Director in the same University responsible for Students Industrial work Experience Scheme. Dr. Mrs. Bertha Abdu Danja has attened conferences in USA, Europe, and here in Nigeria.

Abstract:

Quality of water is an important criterion for evaluating the suitability of water for drinking that is why this research is fused on the quality of different sources of drinking water in Kashere. Most people in this area do not have portable water as the source of their drinking water, so they make do with every type of water available.

The ground water samples were collected and subjected for a comprehensive physico – chemical analysis. The following  parameters were tested, i.e. pH, Electrical Conductivity, Alkalinity, Total hardness, Total Dissolved Solids, phosphate, sulphate, chloride, nitrate, manganese, iron, nickel, arsenic, copper and flouride. On comparing the results against drinking water quality standards laid by World Health Organization and Nigerian Standard Organization, it was found that the water quality parameters were within the permissible limit, but some were not. The conclusion this project has reached, is that based on available laboratory equipments most parameters were within given limit but more detail research need to be carried out to test for more parameters than this work did, to ascertain the quality of these drinking water.

Biography:

Gomaa El Fawal has completed his PhD from Zagazig University, Egypt and postdoctoral studies from “Center for Rapid and Sustainable Product Development (CDRsp) - Polytechnic Institute of Leiria (IPL), Leiria, Portugal”. He works as a researcher at Advanced Technologies and New Materials Research Institute (ATNMRI), Scientific Research and Technological Applications City (SRTA-City), Alexandria, Egypt. He has published more than 15 papers in reputed journals and has been serving as a reviewer member of repute.

Abstract:

       Electrospinning is an efficient technique to produce ultrafine polymeric fibers. It has gained a  great scientific and industrial interest due to its cost-efficiency, versatility, and potential to be utilized in a wide range of applications. We used electrospinning to produce nanofibers from cellulose acetate (CA) and polyethylene oxide (PEO) polymers loaded with different concentrations of disulfiram (DS) for further implementing in anticancer treatment. Various tests were carried out including scanning electron microscopy (SEM), FTIR, and thermal gravimetric analysis (TGA) to evaluate the efficiency of the prepared fibers as anticancer material. On the other hand, it revealed a potent apoptotic-dependent anticancer activity against human colon and breast cancer cells with minimal toxicity on human normal cells. Hence, the studied fiber was able to overcome one of the major existing obstacles for using DS as an anticancer drug by decreasing its toxicity against healthy cells. The current approach corroborated that PEO/CA nanofibers loaded by disulfiram could be applied as a promising safe candidate for anticancer treatment..

Biography:

Dr. Kiramat Shah is Assistant Professor at Institute of Chemical Sciences, University of Swat, Swat KPK Pakistan. He has obtained his Ph.D degree from International Center for Chemical and Biological Sciences University of Karachi, Karachi Pakistan. He is synthesizing macrocycles and macromolecules using different advanced reactions particularly Azide -Alkyne Click reaction, Glaser coupling, Sonogashira coupling, amide bond formation using coupling reagents and Mannich reaction. For the characterization of these molecules we use different techniques like 1H NMR, 13C NMR, advanced 2D NMR, EI-MS, ESI-MS, MALDI, UV-vis and FT-IR spectroscopy. To explore the chemo-sensing properties of these macrocycles and macromolecules for different antibiotics, dyes, explosives and metal ions we use UV-visible and Fluorescence spectroscopy.

Abstract:

The monitoring of pharmaceutical drugs in the environment is of great importance word wide. For

example, in Karachi Pakistan due to contaminated water six children were died and about 200 were fill ill in 2005. A large number of pharmaceutical drugs in highly alarming amount were found in different components of drinking water (surface water, drainage, and effluent) of Karachi in the microgram-per-liter range during bioassay directed chemical analysis. The photophysical evaluation of supramolecular organic molecules as optical probes for detection of water toxins has been recognized to be very selective, sensitive, and economical as compared to the previously used methodologies.

Synthesis, characterization and molecular recognition properties of fluorene based supramolecular cleft is

reported. The cleft molecule was prepared in a single-step with good yield (85% yield), by linking Fluorene

with 1-ethyl piperazine. The cleft molecule was carefully characterized using various spectroscopic techniques such as NMR and mass spectrometry. The supramolecular interaction of cleft with amoxicillin, 6APA, aspirin, captopril, cefotaxime, ceftriaxone, cefuroxime, diclofenac, penicillin, and cephradine was evaluated by fluorescent spectroscopy. The molecular recognition studies showed that amoxicillin selectively binds with cleft in the presence of other drugs. The analytical method developed for the supramolecular interaction of molecular cleft and amoxicillin was validated at varying pH, concentration and temperature during recognition process. Job's plots indicated that the stochiometry of the interactions between the cleft and the amoxicillin was 1:1.

Biography:

Qixing Zhou has completed his Ph.D at the age of 27 years from Chinese Academy of Sciences. He is Yangtze River Scholar, National Outstanding Youth Science Fund winner, the director of the Centre of Environmental Sciences, Professor in Environmental Sciences, Nankai University, China. He has published more than 500 papers in reputed journals and has been serving as an editorial board member in many international journals.

Abstract:

Chemical pollution mainly refers to the pollution caused by agricultural chemicals, food additives, food packaging containers and industrial wastes, such as mercury, cadmium, lead, cyanide, organic phosphorus and other organic or inorganic compounds, namely, environmental pollution caused by the entry of chemicals or chemical pollutants into the environment. These chemicals involve in organic and inorganic substances, most of which are artificially produced by human activities. It is shown that about 140 chemicals have a carcinogenic effect on animals, in particular, there are about 40 human carcinogens and suspected carcinogens. About 80-85% of human cancer cases are associated with chemical carcinogens. In this report, 12 important chemicals that can induce cancer, including formaldehyde, acetaldehyde, tetrachloroethylene, and propylene epoxide will be analyzed and summarized, in particular, 8 emerging chemical pollutants with carcinogenic effects will be firstly expounded.

Biography:

Rafael Silva Oliveira, has completed his Bachelor’s Degree at the age of 21 years from Instituto Luterano de Ensino Superior de Itumbiara. He is a laboratory analyst at one of the biggest dairy companys in Brazil. He leads the laboratory of the Itumbiara plant, with effective participation in the study and implementation of analytical methodologies and quality systems in laboratories, focusing on the improvement and optimization of analytical processes and continuous quality improvement.

Abstract:

The water is a very important natural resource for life in Earth. It is fundamental for several human activities, and more for the food industries, were we have the high consumption in dairy industries, the focus of this project. This present study was developed with the objective of proving the technical and financial viability of a model for reutilization of residual water from a dairy plant, through the coagulation with aluminum sulfate and disinfection with sodium hypochlorite. Thus, a data collection on water consumption and generation of effluents in the industry was carried out, as well the treatment of residual water through Jar-Test, followed by a physical-chemical and microbiological analyzes of water after treatment. The aluminum sulfate test was efficient in the residual water treatment, with a turbidity reduction efficiency of 97,6%. Also the disinfection test with sodium hypochlorite was efficient with the dosages of 1,0, 1,5 and 2,0 ppm and 30 minutes of contact time, which resulted in absence of total coliforms and Escherichia coli, for all samples. The studies parameters had good results to the treatment, which make new perspectives for the reuse of water in dairy plant, which makes possible to reduce the processing costs with the purchase of water and consequently less environmental impact to the water resources.

Biography:

B. Lorestani has completed his PhD at the age of 30 years from Tehran university. She is postdoctoral student now. she is associated professor in Department of Environmental science, College of Basic Sciences, Hamedan Branch, Islamic Azad University. She has teached environmental pollution for PhD and masters students. She has published more than 20 papers in ISI journals.

Abstract:

 The objective of the present study is to investigate the current status of heavy metal pollution around Buali industrial town; Hamadan, western Iran. The concentrations of 9 important heavy metals such as arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel and zinc have been evaluated in ground water samples during May 2017. To evaluate the suitability of water for aquatic life and drinking purposes, the indices of Heavy metal evaluation (HEI), heavy metal pollution (HPI) and contamination (Cd) were computed. The results indicated that, the order of the mean concentrations of heavy metals was recorded to be Pb> Ni > Cr > Fe > Cd > As >Mn, Cu, Zn with respect to Cd index. The mean HEI and HPI values are 89.1 and 881.8 respectively, associated with high risks, where, the studied metals exceeded the drinking water and aquatic life limits.

Biography:

Ojah Emmanuel Onah is a doctoral student of the department of chemistry, University of Ibadan, Nigeria. He obtained his M.Sc. from the university of Ibadan, Nigeria in 2016.His masters research work was published last year in Journal of Alternative and complementary Medical reseach.

Abstract:

Aims: To screen hexane, ethyl acetate and methanol fractions of the methanol extract of Spathodea campanulata leaves for secondary metabolites, to isolate and to characterize constituents of the ethyl acetate fraction using GC-MS and IR and to determine the antioxidant activities of the three fractions.

Methodology: Methanol extract of Spathodea campanulata leaves was obtained by cold extraction, and partitioned into hexane, ethyl acetate and methanol fractions. Phytochemical screenings of the fractions were carried out using standard procedures to identify the class of constituents present in each of them. Ethyl acetate fraction was subjected to column chromatographic separations by gradient elution, and isolates were TMS (Trimethylsilyl) derivatised and characterized by GC-MS (Gas chromatography-mass spectrometry). Antioxidant content was also evaluated on the three fractions using 2, 2-diphenyl-picrylhydrazyl (DPPH) freeradicalscavenging method. Percentage of inhibition and IC50 values were obtained for each

fraction.

Results: Phytochemical screenings revealed presence of alkaloids, tannins, saponin, resins, phenol, cardiac glycosides, steroids, flavonoids, anthraquinones and terpenoids in the three fractions in varying concentrations. Alkaloids, resins, phenol and cardiac glycosides were found to be intense in the three fractions while phylobatannin was found to be absent in all the three fractions. Three compounds isolated from the ethyl acetate fraction were characterized based on MS and IR spectral interpretations as palmitic acid, ethylamine and caffeic acid. Percentage of inhibition of the three fractions indicates that they have substantial antioxidant activity with the standards at high concentration of 250 to 1000 μg/mL. The hexane fraction has the highest antioxidant activity with an IC50 of 178.46 μg/mL when compared to other fractions.

Conclusion: This paper reports phytochemical constituents and high antioxidant activity (at

concentrations of 250 μg/ mL and above) of the African tulip tree (Spathodea campanulata) when

compared to the standards. This has not been earlier reported in literature, our results supports its

wide ethno-medicinal applications.

Biography:

M. Cheraghi has completed his PhD at the age of 32 years from Tehran university. He is postdoctoral student now. He is associated professor in Department of Environmental science, College of Basic Sciences, Hamedan Branch, Islamic Azad University. He has teached environmental pollution for PhD and masters students. He has published more than 25 papers in ISI journals. This paper is related to my PhD student thesis.

Abstract:

The present study describes the preparation and capability of the low-cost graphene oxide/almond shell (GO@AS) composite by a freeze-drying method. The composite showed excellent ability to uptake the nickel and cadmium ions which were characterized by FTIR and SEM techniques. The optimized values of pH, contact time and adsorbent doses were found to be 7.5, 1-3 h and 0.1 g, respectively. Also, adsorption isotherms of metal ions on adsorbents were determined and correlated with common isotherm equations such as Langmuir and Freundlich models. The obtained correlation coefficient (R²) for different adsorbents (GO and GO@AS composite) suggested well-fitting of the experimental data to Langmuir isotherm for Ni²⁺ and Cd²⁺ ions (except adsorption of Cd²⁺ ion on the surface of GO). The maximum sorption capacities of GO@AS calculated from Langmuir isotherm model were 113.63 mg g^-1 for Cd(II) and 64.10 mg g^-1 for Ni(II). Interestingly, it was found that much higher adsorption capacity was achieved for Cd(II) on GO@AS than that for Ni(II) adsorption.

Biography:

She has received B.S of pharmaceutical sciences from faculty of pharmacy, Cairo. university. She is currently a master student at the same faculty. Her research includes the use of nano formulations to improve the dermal retention of drugs. My research interests are in the area of nano pharmaceuticals, pharmacokinetics and drug delivery, drug targeting and pharmaceutical technology. The aim is to improve the patient's quality of life.

Abstract:

The aim of this study was to determine the ability of polymeric micelles to successfully deposit into skin layers using HPLC. Polymeric micelles were prepared using pluronic L-121 (25 %) and pluronic F-127 (75 %). Entrapment efficiency, particle size, polydispersity index and zeta potential of the formula were 99.5 ± 0.5%, 48.9 ±  7.39 nm, 0.454 ± 0.03 and _12.3 ± 0.707 mV, respectively. The calibration curve of BDP was constructed using HPLC in 1:1 (v/v) mixture of ethanol: water and the detection wavelength was 254 nm. The mobile phase consisted of acetonitrile: water (70:30) delivered at flow rate of 1 ml/min. The assay validation was performed in terms of linearity, precision, specificity and accuracy. Ex-vivo studies were performed using Franz-cell setup to compare skin deposition of Beclomethasone dipropionate (BDP) mixed micelles and the commercial product. At the end of the permeation experiment, the skin was demounted from the set up and washed with saline for 20 seconds to remove any residual drug. Then the skin was cut into small pieces and subjected to a thorough extraction for the efficient extraction of BDP from the skin. The solution was analyzed using HPLC to determine the amount of dug deposited into the skin. The local accumulation efficiency (LAC) values for BDP were calculated by dividing the amount of the drug deposited into the skin by the total amount permeated at the end of the experiment. The amount of BDP retained into the skin after 6 hrs in case of the commercial formula was 204.42 ± 37.92 ug/cm², while that of mixed micelles was 632.52 ± 15.59 ug/cm². The calculated LAC ratio was found to be in case of mixed micelles 7.78.The LAC ratio was significantly higher than the brand formula having a LAC ratio of 0.33(p<0.05).This confirms the enhancement of drug deposition accompanied by a decrease in the amount permeated into the systemic circulation in case of polymeric micelles These results revealed that polymeric micelles could be a promising tool for enhanced delivery of poorly soluble drugs and that HPLC can be used as an efficient method for the determination of drugs deposited into the skin.

Biography:

Dr. Makama is an outstanding scientist in the field of Organic/Medicinal Chemistry. He is an advanced degree professional in this field by virtue of his Ph. D. from the University of Reading, White-knights United Kingdom. Dr. Makama has over 15 years of professional experience in teaching/chemical laboratories in diversified areas and roles. He is a chemist with extensive experience in various methodologies of medicinal chemistry, natural products isolation and drug discovery, including organic synthesis, structure-activity relationship (SAR) studies, lead compound optimization, and assay development. Dr. Makama’s work revolves around synthetic methodologies and their application in the Synthesis of Natural Products. Dr. Makama also has interest in the Lewis acids catalyzed Homogenous Transesterification of waste oil; an efficient strategy for the production of biodiesel. Dr. Makama is also involved in the area of isolation and characterization of active compounds for medicinal purposes especially: The anti neuro-degenerative disorders and the anti-cancer approach.

Abstract:

The work reported here in is primarily concerned with the synthetic approaches to the tricyclic core 2 in brasoside 1 isolated from Verbena littoralis, a plant which has been widely used in a traditional folk medicine in South America for treating diarrhoea, typhoid fever and tonsillitis.  More recently, the crude extract of V. littoralis has been shown to potentiate NGF-induced neurite outgrowth from PC12D cells.¹ A synthetic approach based on carbonyl-ene reaction has been examined to prepare the bicyclic core in the natural product. An ongoing asymmetric synthesis of the tricyclic core 2 was forged from common and relatively cheap intermediate which was rapidly assembled using stereo- controlled reduction, with L-selectride and a further formylation protocol.  

                 Reagents and conditions: a) L-selectride , THF, 78%; b) KMnO₄, KOH, H₂O, 82%; c) ethyl formate, dry ether, 54%                                                

Application of both [2+2] cycloaddition and Baeyer-Villager oxidation has enabled to access stereo-selectively substituted bicylic-adducts derivatives for use in synthetic modifications.²   

Biography:

Sair said prepare is persuing his PhD  from University  HASSAN II of Casablanca. He  has  published  more than 8 papers in reputed journals and has been serving as an editorial board member of repute.

Abstract:

Insulation is considered one of the effective solutions to achieve energy savings in building and thermal energy storage systems. Better insulation having low thermal conductivity contributes significantly to new construction and retrofitting existing buildings. Numerous analytical expressions for estimation of effective thermal conductivity of composite materials have been proposed by several authors. Basic expressions apply to spherical filler particles but later models were developed to allow the inclusion of other particle shapes, the presence of particle coating and the interfacial thermal resistance. Models belonging to the class of effective medium approximations usually fail to predict the properties of a multiphase material close to and above the percolation threshold. In the present paper, a novel and efficient model was developed for predicting the effective thermal conductivity of the composite materials based of polymers matrix and natural fibers at different filler percentages. By introducing the relative radius as a parameter, the effective thermal conductivity can be predicted precisely when the thermal properties of filler and matrix are prescribed. The model employed the resistor network strategy to achieve a highly efficient prediction during the overall conductivity calculation. To verify this model, a wide range of composites were analyzed using lambda meter apparatus. The model-based simulation values showed good agreement with the experimental results. Moreover, a discussion on the effects of the newly-introduced parameter was given. Finally, the relationship between the fibers content percentage and the thermal conductivity of the composite was studied.