Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend 9th Global Chemistry Congress Lisbon, Portugal.

Day 1 :

Keynote Forum

Marek Trojanowicz

Institute of Nuclear Chemistry and Technology, Warsaw, Poland, and Department of Chemistry, University of Warsaw, Poland

Keynote: Flow Chemistry: Flow Analysis vs. Flow Synthesis - Similarities and Current Trends
Chemistry  Congress 2018 International Conference Keynote Speaker Marek Trojanowicz photo
Biography:

Marek Trojanowicz is Professor of Chemistry in the Institute of Nuclear Chemistry and Technology in Warsaw, Poland, and professor emeritus of the Department of Chemistry, University of Warsaw. His expertise includes  flow analysis, liquid chromatography and capillary electrophoresis, design of electrochemical sensors and biosensors, application of ionizing radiation for water and waste treatment and application of chemical analysis in archaeometry. He was granted Visiting Professor positions in numerous universities all over the world including long-term appointments in University of Michigan, University of California at Riverside, University of Tasmania, Australia, Okayama University, Japan, and University of Sao Paulo, Brazil. He is author of 350 scientific papers, 2 monographic books and editor of 2 books in the field of flow analysis and automation of analytical measurements. He is a member of advisory boards of 10 international analytical journals. His current number of citations according to ISI Web of Knowledge is almost 6000, and Hirsch index 40.

 

Abstract:

During last two decades, flow chemistry has been a very intensively developing field of modern methods of chemical synthesis on a laboratory scale. What is particularly interesting, the development on numerous techniques and methods in flow chemistry, has practically never been referred to the laboratory flow analysis methods developed since the 1950s.            

The efficient and reproducible treatment of samples or chemical transformation of analytes are among commonly recognized attributes of flow analysis. At the same time, this is the fundamental element of synthetic methods in flow chemistry. On the other hand, the monitoring of progress and yield of syntheses under continuous flow conditions, carried out in a discrete mode after a given process in collected fractions, has been increasingly replaced by continuous monitoring with on-line instruments incorporated into flow setups. This is exactly what is considered as a typical application of flow analysis. Other methods in flow analysis, as well as laboratory flow synthesis are being developed in numerous leading research centers on a world scale, hence it is bewildering to find that practical research activity in each of these fields does not involve referring one to another.

The flow mode of conducting chemical syntheses facilitates chemical processes through the use of on-line analytical monitoring of occurring reactions, the application of solid-supported reagents to minimize downstream processing and computerized control systems to perform multi-step sequences. They are exactly the same attributes as those of flow analysis, which has solid place in modern analytical chemistry in several last decades.

 

 

Keynote Forum

Bilge SENER

Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Turkey

Keynote: Drug Discovery of Potential Drug Candidates From Some Turkish Medicinal Plants
Chemistry  Congress 2018 International Conference Keynote Speaker Bilge SENER photo
Biography:

Bilge Sener graduated from Ankara University, Faculty of Pharmacy in 1974. She has completed her PhD awarded by the Turkish Scientific and Technological Research Council (TUBITAK) at the Department of Pharmacognosy in 1977. In 1981, she became an Associate Professor. She was involved within the process of establishing Department of Pharmacognosy, Faculty of Pharmacy, Gazi University in 1982. She became a Full Professor in 1988. She achieved some researches at the Department of Chemistry, The Pennsylvania State University (USA) between 1986 and 1988 as Visiting Scientist awarded by National Science Foundation. She was also involved in several administrative works at Gazi University; as Director at the Department of Pharmacognosy, Faculty of Pharmacy, Gazi University between 1982 and 2002, as Chair at Division of the Professional Sciences of Pharmacy, as Co-Director at the Institute of Health Sciences (1988-1994) and as Dean at the Faculty of Pharmacy, Gazi University (1994-1997). She was given the degree of Adjunct Professor by University of Karachi, Pakistan. She worked as Director in 48 projects supported by NATO, NSF, IUPAC, Soctrates-Grundtvig, TUBITAK and Universirty Research Funds by now. She has authored or co-authored 7 books, 85 chapters and 658 research articles published in leading international journals. She has also given 68 conferences and 313 plenary and invited lectures at the international symposia in the field of natural product chemistry. She has supervised 5 PhD, 12 MSc at Gazi University as well as co-supervised 17 PhD thesis at the University of Karachi. She is a member for 14 international and national professional societies.

 

Abstract:

Bioresources have tremendous potential in providing bioactive compounds for the development of new leads. There is a great scope for new drug candidates based on traditional medicinal plants throughout the world. Medicinal plants have an enermous potential for producing bioactive compounds of great benefit to mankind. The achievements in the field of science and technology were resulted in the isolation of pure compounds such as morphine, quinine, digoxin, atropine, ephedrine, reserpine, galanthamine and taxol were used in clinic. Some compounds like diosgenin can also be used to obtain steroidal compounds (cortisone, hormones) as starting compound. The number of drugs derived from medicinal plants that are recently introduced into clinical use is increasing. Besides, numberous of standardized herbal extracts were approved by the health authorities to be used in phytotherapy as phytomedicines.
Turkey is one of the rich countries in terms of bioresources depends on different climates, geographical location, ecological factors and aquatic environments as well as the passageway between Europe, Asia and Africa. Therfore the floristic diversity provides a wide choise of species represented 12.000 taxa of which 3700 is endemic. Turkey is a party to the Convention on Biological Diversity which states that participating countries have sovereign rights over their own bioresources.
The drug discovery program from nature in our laboratory involves several steps from plant collection, extraction, HTS of the extracts by using in vitro enzyme inhibitory tests, bioassay-guided fractionation through the isolation, structure elucidation of bioactive compounds. We found diverse classes of compounds ranging from simple aromatics to complex molecules of alkaloids, terpenoids, steroids and phenylpropanoids showed significant biological activities including anticholinergic, anticholinesterase, antiinflammatory, antimalarial, antituberculosis and antiprotozoal from Amaryllidaceae, Liliaceae, Iridaceae, Buxaceae, Fumariaceae, Taxaceae etc. plant families. The investigation of these sources requires multidisciplinary approach in the discovery and development process. In this presentation, selected Turkish medicinal plants that possess several bioactivities alongwith some drug candidates have been summarized.