9^th Global Chemistry Congress

Biography

Biography: Steffen Eller

Abstract

The driver for medicinal chemistry is the demand for innovative medicines. Typically the growing need for novel active ingredients is accompanied by the search for targeted molecular diversity and novel experimental routes resulting in an increase of the synthetic work with the same amount of human resources. The only way to cope with this catch22 are flexible, modular, uncompromising automated solutions for library synthesis.

 

Following a brief introduction to concepts and Chemspeed’s innovation enabling technology, this presentation will focus on selected case studies from our customer portfolio such as:

 

• Synthesis of a triazole library using automated click chemistry.
• Development of a first generation MKP-1 probe.
• Discovery of an α-amino C–H arylation reaction using the strategy of accelerated serendipity.
• Synthesis of an oxazolidinones library using solid phase organic synthesis.
• Development of nanoparticle drug discovery vehicles.